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Circulation: Cardiovascular Interventions
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Published Online
on February 20, 2009

Circulation: Cardiovascular Interventions. 2009
Published online before print February 20, 2009, doi: 10.1161/CIRCINTERVENTIONS.108.814046
A more recent version of this article appeared on April 1, 2009
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Original Article

Percutaneous Closure of Atrial Septal Defects: Echocardiographic and Functional Results in Elderly Patients over 60 Years

Smita R. Jategaonkar; Werner Scholtz; Henning Schmidt and Dieter Horstkotte1

Ruhr University Bochum

1 E-mail: akohlstaedt{at}hdz-nrw.de

Background—Percutaneous closure of atrial septal defects (ASD) is well established in children and adults and found to improve symptoms and positively influence right-heart remodelling. The aim of this study was to evaluate the efficacy and long-term outcome in adult patients older than 60 years.

Methods and Results—96 patients in the age group of 60 - 84 years were included in this study. Percutaneous closure was performed effectively in all patients. Functional capacity according to the New York Heart Association (NYHA) and peak oxygen uptake in the cardiopulmonary exercise testing (CPX) improved significantly after ASD closure, especially in patients with a Qp:Qs > 2. Echocardiographic measurements of the right ventricular enddiastolic diameter showed a significant decrease. No device associated complications were observed, but in 16 patients paroxysmal atrial fibrillation (AF) occurred after device implantation.

Conclusions—Percutaneous ASD closure can be performed safely and with minimal risk even in elderly patients. They profit in terms of symptom-reduction, improvement of exercise capacity and right-heart remodelling.

Key Words: catheterization • heart septal defects • atrial septal defect • elderly


Related Articles

Not Just Big Kids: Closing Atrial Septal Defects in Adults Older Than 60 Years
Giuseppe Martucci and Michael Landzberg
Circ Cardiovasc Interv 2009 2: 83-84. [Extract] [Full Text] [PDF]

Percutaneous Closure of Atrial Septal Defects: Echocardiographic and Functional Results in Patients Older Than 60 Years
Smita Jategaonkar, Werner Scholtz, Henning Schmidt, and Dieter Horstkotte
Circ Cardiovasc Interv 2009 2: 85-89. [Abstract] [Full Text] [PDF]



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Home page
Circ Cardiovasc IntervHome page
G. Martucci and M. Landzberg
Not Just Big Kids: Closing Atrial Septal Defects in Adults Older Than 60 Years
Circ Cardiovasc Interv, April 1, 2009; 2(2): 83 - 84.
[Full Text] [PDF]