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Original Article |
Ruhr University Bochum
1 E-mail: akohlstaedt{at}hdz-nrw.de
Background—Percutaneous closure of atrial septal defects (ASD) is well established in children and adults and found to improve symptoms and positively influence right-heart remodelling. The aim of this study was to evaluate the efficacy and long-term outcome in adult patients older than 60 years.
Methods and Results—96 patients in the age group of 60 - 84 years were included in this study. Percutaneous closure was performed effectively in all patients. Functional capacity according to the New York Heart Association (NYHA) and peak oxygen uptake in the cardiopulmonary exercise testing (CPX) improved significantly after ASD closure, especially in patients with a Qp:Qs > 2. Echocardiographic measurements of the right ventricular enddiastolic diameter showed a significant decrease. No device associated complications were observed, but in 16 patients paroxysmal atrial fibrillation (AF) occurred after device implantation.
Conclusions—Percutaneous ASD closure can be performed safely and with minimal risk even in elderly patients. They profit in terms of symptom-reduction, improvement of exercise capacity and right-heart remodelling.
Key Words: catheterization heart septal defects atrial septal defect elderly
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G. Martucci and M. Landzberg Not Just Big Kids: Closing Atrial Septal Defects in Adults Older Than 60 Years Circ Cardiovasc Interv, April 1, 2009; 2(2): 83 - 84. [Full Text] [PDF] |
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