This Article Full Text Full Text (PDF) Data Supplement Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Linke, A. Articles by Schuler, G. Search for Related Content PubMed Articles by Linke, A. Articles by Schuler, G. Related Collections Catheter-based coronary and valvular interventions: other Echocardiography CV surgery: aortic and vascular disease Other Research

Images and Case Reports in Interventional Cardiology

Ingrowths of a Percutaneously Implanted Aortic Valve Prosthesis (CoreValve) in a Patient With Severe Aortic Stenosis

Axel Linke, MD; Robert Höllriegel, MD; Thomas Walther, MD; Katrin Schierle, MD; Christian Wittekind, MD; Jörg Ender, MD; Friedrich W. Mohr, MD and Gerhard Schuler, MD

From the Departments of Cardiology (A.L., R.H., G.S.), Cardiac Surgery (T.W., F.W.M.), Anesthesiology (J.E.), and Pathology (K.S., C.W), Heart Center, University of Leipzig, Leipzig, Germany.

Correspondence to Axel Linke, MD, Heart Center, University of Leipzig, Strümpellstrasse 39, 04289 Leipzig, Germany. E-mail linkea@medizin.uni-leipzig.de

An extract of the first 250 words of the full text is provided, because this article has no abstract.

An 80-year-old woman was admitted to our institution because of shortness of breath (New York Heart Association grade III) and stable angina pectoris (Canadian Cardiovascular Society [CCS] grade II).

Two years ago, the patient had a posterior wall infarction successfully treated by percutaneous coronary intervention and stent implantation. A low-gradient aortic stenosis with an aortic valve area of 1.1 cm² was also diagnosed but was considered to be clinically insignificant at the time.

Because of the progression of symptoms within the last 2 years, a re-evaluation of coronary and aortic valve disease was performed. Coronary angiography revealed a 1-vessel coronary disease with a patent stent in the right coronary artery without any evidence of restenosis. The left ventricular ejection fraction was only moderately impaired (55%). However, the aortic valve area, as determined invasively, had decreased to 0.5 cm². This was confirmed by echocardiography; the cusps of the aortic valve were calcified and their motion was impaired (Supplemental Data Movie 1).

On the basis of these findings, the necessity of an aortic valve replacement was discussed. However, because the patient was anxious and refused conventional aortic valve replacement, percutaneous treatment of the aortic stenosis using the second generation of the CoreValve ReValving system (CoreValve Inc, Irvine, Calif) was proposed¹ (Figure 1A). This prosthesis has an inner diameter of 23 mm and consists of a self-expanding nitinol frame, which carries 3 leaflets of porcine pericardial tissue. The upper part of the frame anchors the system in the aorta; the . . . [Full Text of this Article]

This article has been cited by other articles:

				S. R. Dixon, C. L. Grines, and W. W. O'Neill The year in interventional cardiology. J. Am. Coll. Cardiol., June 2, 2009; 53(22): 2080 - 2097. [Full Text] [PDF]