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Circulation: Cardiovascular Interventions
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Published Online
on September 3, 2008

Circulation: Cardiovascular Interventions. 2008
Published online before print September 3, 2008, doi: 10.1161/CIRCINTERVENTIONS.108.768176
A more recent version of this article appeared on October 1, 2008
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Original Article

Implementation of Guidelines for the Treatment of Acute ST-Elevation Myocardial Infarction – the Cologne Infarction Model (KIM) Registry

Markus Flesch1,9; Jens Hagemeister1; Hans-Joerg Berger2; Annett Schiefer3; Sylke Schynkowski1; Martin Klein1; Sassab Sahebdjani3; Stephan vom Dahl3; Wolfgang Fehske4; Rudolf Mies5; Michael von Eiff6; Holger Pfaff7; Peter Frommolt8 and Hans-Wilhelm Hoepp1

1 Klinik III für Innere Medizin, University of Cologne;
2 Krankenhaus Merheim, University of Cologne;
3 St. Franziskus Krankenhaus, University of Cologne;
4 St. Vincenz-Hospital Cologne;
5 St. Antonius-Krankenhaus Cologne;
6 Malteser-Krankenhaus St. Hildegardis Cologne;
7 Zentrum für Versorgungsforschung, University of Cologne;
8 Institut für Medizinische Statistik, Informatik und Epidemiologie, University of Cologne

9 E-mail: markus.flesch{at}uni-koeln.de

Background—Aim of the Cologne Infarction Model (KIM) is to examine the feasibility of obligatory treatment of STEMI by first line percutaneous coronary intervention.

Methods and Results—The study was performed in Cologne with >1 million citizens, 5 coronary intervention centres and 11 primary care hospitals. 12-lead ECG is available for all EMS teams. Partners guaranteed direct transfer of STEMI patients to a catheterization laboratory. In 2006, 519 patients were included. 24% presented at a primary care hospital, 11% directly at a coronary intervention centre, 5% were transferred by EMS to primary care hospitals, 60% were directly transferred by EMS to a catheterization laboratory. In 91% of cases, the catheterization laboratory was notified of the patient's arrival in advance. False positive ECG diagnosis of STEMI by EMS accounted for 6%. Median treatment times were: begin of symptoms to first medical contact 120 minutes, phone-to-balloon 70 minutes, and door-to-balloon 49 minutes. 93% of all patients underwent angiography. 409 patients were treated by coronary intervention, 24 underwent emergency CABG. TIMI 3 flow was obtained in 89%. In hospital, deaths and new myocardial infarctions were observed in 12.1 % and in 1.9 % of all patients, respectively.

Conclusion—KIM provides evidence for the feasibility of obligatory treatment of STEMI by primary coronary intervention in a metropolitan setting. Acceptance of treatment pathways allowed nearly all STEMI patients to undergo coronary angiography. ECG competence of EMS was excellent. Treatment times were within postulated limits. Results including mortality were within a high quality range.

Key Words: angioplasty • catheterization • myocardial infarction • emergency service • guideline


Related Article

Implementation of Guidelines for the Treatment of Acute ST-Elevation Myocardial Infarction: The Cologne Infarction Model Registry
Markus Flesch, Jens Hagemeister, Hans-Joerg Berger, Annett Schiefer, Sylke Schynkowski, Martin Klein, Sassan Sahebdjami, Stephan vom Dahl, Wolfgang Fehske, Rudolf Mies, Michael von Eiff, Holger Pfaff, Peter Frommolt, and Hans-Wilhelm Hoepp
Circ Cardiovasc Interv 2008 1: 95-102. [Abstract] [Full Text] [PDF]



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