Published Online
on February 10, 2009

A more recent version of this article appeared on February 1, 2009

This Article Full Text (PDF) All Versions of this Article: 2/1/20    most recent CIRCINTERVENTIONS.108.826172v1 Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Singh, M. Articles by Holmes, D. R. Search for Related Content PubMed Articles by Singh, M. Articles by Holmes, D. R. Related Collections Catheter-based coronary interventions: stents Related Article

Original Article

Trends in the Association between Age and In-Hospital Mortality Following PCI: National Cardiovascular Data Registry Experience

Mandeep Singh^1,8; Eric D. Peterson²; Matthew T. Roe²; Fang-Shu Ou²; John A. Spertus³; John S. Rumsfeld⁴; H. Vernon Anderson⁵; Lloyd W. Klein⁶; Kalon K.L. Ho⁷ and David R. Holmes¹

¹ Mayo Clinic, Rochester, MN;
² Duke University Medical Center, Durham, NC;
³ Mid America Heart Institute, Kansas City, MO;
⁴ Denver VA Medical Center, Denver, CO;
⁵ University of Texas Health Science Center, Houston, TX;
⁶ Rush Medical Center, Chicago, IL;
⁷ Beth Israel Deaconess Medical Center, Boston, MA

⁸ E-mail: singh.mandeep{at}mayo.edu

Background—Temporal trends and contemporary data characterizing the impact of patient age on in-hospital outcomes of percutaneous coronary interventions (PCI) are lacking. We sought to determine the importance of age by assessing the in hospital mortality of stratified age groups in the National Cardiovascular Database Registry (NCDR).

Methods and Results—In-hospital mortality following PCI on 1,410,069 patients was age-stratified into 4 groups, Group 1 (age<40, n=25,679), Group 2 (40-59, n=496,204), Group 3 (60-79, n=732,574), and Group 4 (80, n=155,612), admitted from January 1st 2001 to December 31st 2006. Overall in-hospital mortality was 1.22%, and was 0.60%, 0.59%, 1.26%, and 3.16% in groups 1 to 4 respectively, p<0.0001. Overall temporal improvement per calendar year in the adjusted in-hospital mortality following PCI was noted in most groups, however, this finding was significant only in the two older age groups, group 3 (OR 0.94, 95% CI 0.92, 0.96) and group 4 (OR 0.95, 95% CI 0.92, 0.97). The absolute mortality reduction was greatest in the most elderly group, those over the age of 80 years.

Conclusions—In-hospital mortality following PCI has fallen for all age groups over the last six years. However, the largest absolute reduction was seen among patients 80 years of age or older.

Key Words: aging • angioplasty • mortality

Related Article

Trends in the Association Between Age and In-Hospital Mortality After Percutaneous Coronary Intervention: National Cardiovascular Data Registry Experience

Mandeep Singh, Eric D. Peterson, Matthew T. Roe, Fang-Shu Ou, John A. Spertus, John S. Rumsfeld, H. Vernon Anderson, Lloyd W. Klein, Kalon K.L. Ho, and David R. Holmes
Circ Cardiovasc Interv 2009 2: 20-26. [Abstract] [Full Text] [PDF]