A New Challenger Against the CHAMPION?
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- arterial pressure
- heart failure
- microelectricalmechanical systems
- wireless technology
MEMS stands for microelectromechanical systems and represents the devices that integrate microcomponents such as sensors and actuators on a single chip. The MEMS technology changed our world dramatically, and now MEMS can be found in many places around us including airbags, inkjet printers, game controllers, and smart phones to name a few. Integration of MEMS within biomedicine is known as Bio-MEMS,1 and its representative application is a pacemaker. More recently, by taking advantages of miniaturization, high sensitivity, wireless technology, and low energy requirement, MEMS use for implantable pressure sensor has emerged as a new approach to continuously and noninvasively monitor pressures inside the body. CardioMEMS is the first US Food and Drug Administration–approved heart failure (HF) monitoring sensor that allows ambulatory monitoring of pulmonary arterial pressure by implanting the device into the pulmonary arterial branch.
See Article by Mondritzki et al
CHAMPION trial (CardioMEMS Heart Sensor Allows Monitoring of Pressure to Improve Outcomes in NYHA Class III Heart Failure Patients) examined the effectiveness of CardioMEMS in chronic HF patients. In detail, the CHAMPION trial was a randomized controlled, single-blind study that investigated the benefit of ambulatory pulmonary artery pressure–guided management of HF in 550 patients with New York Heart Association functional class III HF. The study demonstrated 37% reduction in HF–related hospitalization in the CardioMEMS monitoring group compared with a matched control group during a follow-up period of 15 months.2 This study was the first to show reduction in HF events with ambulatory monitoring and prompted further development of hemodynamic monitoring devices. An implantable monitoring device that measures …