Skip to main content
  • American Heart Association
  • Science Volunteer
  • Warning Signs
  • Advanced Search
  • Donate

  • Home
  • About this Journal
    • Editorial Board
    • General Statistics
    • Information for Advertisers
    • Author Reprints
    • Commercial Reprints
    • Customer Service and Ordering Information
  • All Issues
  • Subjects
    • All Subjects
    • Arrhythmia and Electrophysiology
    • Basic, Translational, and Clinical Research
    • Critical Care and Resuscitation
    • Epidemiology, Lifestyle, and Prevention
    • Genetics
    • Heart Failure and Cardiac Disease
    • Hypertension
    • Imaging and Diagnostic Testing
    • Intervention, Surgery, Transplantation
    • Quality and Outcomes
    • Stroke
    • Vascular Disease
  • Browse Features
    • AHA Guidelines and Statements
    • Advances in Interventional Cardiology
    • Case Reports in Interventional Cardiology
    • Clinical Dilemmas in Cardiovascular Interventions
    • Contemporary Reviews in Interventional Cardiology
  • Resources
    • Instructions for Authors
      • Accepted Manuscripts
      • Revised Manuscripts
    • → Article Types
    • → General Preparation Instructions
    • → Research Guidelines
    • → How to Submit a Manuscript
    • Journal Policies
    • Permissions and Rights Q&A
    • Submission Sites
    • AHA Journals RSS Feeds
    • International Users
    • AHA Newsroom
  • AHA Journals
    • AHA Journals Home
    • Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB)
    • Circulation
    • → Circ: Arrhythmia and Electrophysiology
    • → Circ: Genomic and Precision Medicine
    • → Circ: Cardiovascular Imaging
    • → Circ: Cardiovascular Interventions
    • → Circ: Cardiovascular Quality & Outcomes
    • → Circ: Heart Failure
    • Circulation Research
    • Hypertension
    • Stroke
    • Journal of the American Heart Association

  • My alerts
  • Sign In
  • Join

  • Advanced search

Header Publisher Menu

  • American Heart Association
  • Science Volunteer
  • Warning Signs
  • Advanced Search
  • Donate

Circulation:
Cardiovascular Interventions

  • My alerts
  • Sign In
  • Join

  • Home
  • About this Journal
    • Editorial Board
    • General Statistics
    • Information for Advertisers
    • Author Reprints
    • Commercial Reprints
    • Customer Service and Ordering Information
  • All Issues
  • Subjects
    • All Subjects
    • Arrhythmia and Electrophysiology
    • Basic, Translational, and Clinical Research
    • Critical Care and Resuscitation
    • Epidemiology, Lifestyle, and Prevention
    • Genetics
    • Heart Failure and Cardiac Disease
    • Hypertension
    • Imaging and Diagnostic Testing
    • Intervention, Surgery, Transplantation
    • Quality and Outcomes
    • Stroke
    • Vascular Disease
  • Browse Features
    • AHA Guidelines and Statements
    • Advances in Interventional Cardiology
    • Case Reports in Interventional Cardiology
    • Clinical Dilemmas in Cardiovascular Interventions
    • Contemporary Reviews in Interventional Cardiology
  • Resources
    • Instructions for Authors
    • → Article Types
    • → General Preparation Instructions
    • → Research Guidelines
    • → How to Submit a Manuscript
    • Journal Policies
    • Permissions and Rights Q&A
    • Submission Sites
    • AHA Journals RSS Feeds
    • International Users
    • AHA Newsroom
  • AHA Journals
    • AHA Journals Home
    • Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB)
    • Circulation
    • → Circ: Arrhythmia and Electrophysiology
    • → Circ: Genomic and Precision Medicine
    • → Circ: Cardiovascular Imaging
    • → Circ: Cardiovascular Interventions
    • → Circ: Cardiovascular Quality & Outcomes
    • → Circ: Heart Failure
    • Circulation Research
    • Hypertension
    • Stroke
    • Journal of the American Heart Association
Original Article

First Serial Assessment at 6 Months and 2 Years of the Second Generation of Absorb Everolimus-Eluting Bioresorbable Vascular Scaffold

A Multi-Imaging Modality Study

John A. Ormiston, Patrick W. Serruys, Yoshinobu Onuma, Robert-Jan van Geuns, Bernard de Bruyne, Dariusz Dudek, Leif Thuesen, Pieter C. Smits, Bernard Chevalier, Dougal McClean, Jacques Koolen, Stephan Windecker, Robert Whitbourn, Ian Meredith, Cecile Dorange, Susan Veldhof, Karine Miquel Hebert, Richard Rapoza, Hector M. Garcia-Garcia
Download PDF
https://doi.org/10.1161/CIRCINTERVENTIONS.112.971549
Circulation: Cardiovascular Interventions. 2012;CIRCINTERVENTIONS.112.971549
Originally published October 9, 2012
John A. Ormiston
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Patrick W. Serruys
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yoshinobu Onuma
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Robert-Jan van Geuns
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Bernard de Bruyne
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Dariusz Dudek
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Leif Thuesen
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Pieter C. Smits
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Bernard Chevalier
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Dougal McClean
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jacques Koolen
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Stephan Windecker
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Robert Whitbourn
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ian Meredith
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Cecile Dorange
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Susan Veldhof
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Karine Miquel Hebert
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Richard Rapoza
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hector M. Garcia-Garcia
From the Auckland City Hospital, Auckland, New Zealand (J.A.O.); ThoraxCenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., Y.O., R.-J.v.G.); Cardiovascular Center, Aalst, Belgium (B.d.B.); Jagiellonian University, Krakow, Poland (D.D.); Skejby Sygehus University Hospital, Aarhus, Denmark (L.T.); Maasstad Hospital, Rotterdam, the Netherlands (P.C.S.); Institut Jacques Cartier, Massy, France (B.C.); Christchurch Hospital, Christchurch, New Zealand (D.M.C.); Catharina Hospital, Eindhoven, the Netherlands (J.K.); Bern University Hospital, Bern, Switzerland (S.W.); St Vincent’s Hospital, Fitzroy, Australia (R.W.); Monash Cardiovascular Research Centre, Melbourne, Australia (I.M.); Abbott Vascular, Diegem, Belgium (C.D., S.V., K.M.H.); Abbott Vascular, Santa Clara, CA (R.R.); and Cardialysis, Rotterdam, the Netherlands (H.G.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Supplemental Materials
  • Info & Metrics

Jump to

  • Article
  • Supplemental Materials
  • Info & Metrics
  • eLetters
Loading

Abstract

Background—Nonserial observations have shown this bioresorbable scaffold to have no signs of area reduction at 6 months and recovery of vasomotion at 1 year. Serial observations at 6 months and 2 years have to confirm the absence of late restenosis or unfavorable imaging outcomes.

Methods and Results—The ABSORB trial is a multicenter single-arm trial assessing the safety and performance of an everolimus-eluting bioresorbable vascular scaffold. Forty-five patients underwent serial invasive imaging, such as quantitative coronary angiography, intravascular ultrasound, and optical coherence tomography at 6 and 24 months of follow-up. From 6 to 24 months, late luminal loss increased from 0.16±0.18 to 0.27±0.20 mm on quantitative coronary angiography, with an increase in neointima of 0.68±0.43 mm2 on optical coherence tomography and 0.17±0.26 mm2 on intravascular ultrasound. Struts still recognizable on optical coherence tomography at 2 years showed 99% of neointimal coverage with optical and ultrasonic signs of bioresorption accompanied by increase in mean scaffold area compared with baseline (0.54±1.09 mm2 on intravascular ultrasound, P=0.003 and 0.77±1.33 m2 on optical coherence tomography, P=0.016). Two-year major adverse cardiac event rate was 6.8% without any scaffold thrombosis.

Conclusions—This serial analysis of the second generation of the everolimus-eluting bioresorbable vascular scaffold confirmed, at medium term, the safety and efficacy of the new device.

Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00856856.

  • coronary artery disease
  • coronary intervention and bioresorbable scaffold
  • Received January 17, 2012.
  • Accepted July 6, 2012.
  • © 2012 American Heart Association, Inc.
Back to top

Current Issue

Circulation: Cardiovascular Interventions
April 2018, Volume 11, Issue 4
  • Table of Contents

Jump to

  • Article
  • Supplemental Materials
  • Info & Metrics

Article Tools

  • Print
  • Citation Tools
    First Serial Assessment at 6 Months and 2 Years of the Second Generation of Absorb Everolimus-Eluting Bioresorbable Vascular Scaffold
    John A. Ormiston, Patrick W. Serruys, Yoshinobu Onuma, Robert-Jan van Geuns, Bernard de Bruyne, Dariusz Dudek, Leif Thuesen, Pieter C. Smits, Bernard Chevalier, Dougal McClean, Jacques Koolen, Stephan Windecker, Robert Whitbourn, Ian Meredith, Cecile Dorange, Susan Veldhof, Karine Miquel Hebert, Richard Rapoza and Hector M. Garcia-Garcia
    Circulation: Cardiovascular Interventions. 2012;CIRCINTERVENTIONS.112.971549, originally published October 9, 2012
    https://doi.org/10.1161/CIRCINTERVENTIONS.112.971549

    Citation Manager Formats

    • BibTeX
    • Bookends
    • EasyBib
    • EndNote (tagged)
    • EndNote 8 (xml)
    • Medlars
    • Mendeley
    • Papers
    • RefWorks Tagged
    • Ref Manager
    • RIS
    • Zotero
  • Article Alerts
    Log in to Email Alerts with your email address.
  • Save to my folders

Share this Article

  • Email

    Thank you for your interest in spreading the word on Circulation: Cardiovascular Interventions.

    NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

    Enter multiple addresses on separate lines or separate them with commas.
    First Serial Assessment at 6 Months and 2 Years of the Second Generation of Absorb Everolimus-Eluting Bioresorbable Vascular Scaffold
    (Your Name) has sent you a message from Circulation: Cardiovascular Interventions
    (Your Name) thought you would like to see the Circulation: Cardiovascular Interventions web site.
  • Share on Social Media
    First Serial Assessment at 6 Months and 2 Years of the Second Generation of Absorb Everolimus-Eluting Bioresorbable Vascular Scaffold
    John A. Ormiston, Patrick W. Serruys, Yoshinobu Onuma, Robert-Jan van Geuns, Bernard de Bruyne, Dariusz Dudek, Leif Thuesen, Pieter C. Smits, Bernard Chevalier, Dougal McClean, Jacques Koolen, Stephan Windecker, Robert Whitbourn, Ian Meredith, Cecile Dorange, Susan Veldhof, Karine Miquel Hebert, Richard Rapoza and Hector M. Garcia-Garcia
    Circulation: Cardiovascular Interventions. 2012;CIRCINTERVENTIONS.112.971549, originally published October 9, 2012
    https://doi.org/10.1161/CIRCINTERVENTIONS.112.971549
    del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo

Related Articles

Cited By...

Subjects

  • Vascular Disease
    • Restenosis
  • Intervention, Surgery, Transplantation
    • Catheter-Based Coronary and Valvular Interventions

Circulation: Cardiovascular Interventions

  • About Circulation: Cardiovascular Interventions
  • Instructions for Authors
  • AHA CME
  • Guidelines and Statements
  • Permissions
  • Journal Policies
  • Email Alerts
  • Open Access Information
  • AHA Journals RSS
  • AHA Newsroom

Editorial Office Address:
200 Fifth Avenue, Suite 1020
Waltham, MA 02451 
email: circ@circulationjournal.org

Information for:
  • Advertisers
  • Subscribers
  • Subscriber Help
  • Institutions / Librarians
  • Institutional Subscriptions FAQ
  • International Users
American Heart Association Learn and Live
National Center
7272 Greenville Ave.
Dallas, TX 75231

Customer Service

  • 1-800-AHA-USA-1
  • 1-800-242-8721
  • Local Info
  • Contact Us

About Us

Our mission is to build healthier lives, free of cardiovascular diseases and stroke. That single purpose drives all we do. The need for our work is beyond question. Find Out More about the American Heart Association

  • Careers
  • SHOP
  • Latest Heart and Stroke News
  • AHA/ASA Media Newsroom

Our Sites

  • American Heart Association
  • American Stroke Association
  • For Professionals
  • More Sites

Take Action

  • Advocate
  • Donate
  • Planned Giving
  • Volunteer
  • You're the Cure

Online Communities

  • AFib Support
  • Empowered to Serve
  • Garden Community
  • Patient Support Network
  • Professional Online Network

Follow Us:

  • Follow Circulation on Twitter
  • Visit Circulation on Facebook
  • Follow Circulation on Google Plus
  • Follow Circulation on Instagram
  • Follow Circulation on Pinterest
  • Follow Circulation on YouTube
  • Rss Feeds
  • Privacy Policy
  • Copyright
  • Ethics Policy
  • Conflict of Interest Policy
  • Linking Policy
  • Diversity
  • Careers

©2018 American Heart Association, Inc. All rights reserved. Unauthorized use prohibited. The American Heart Association is a qualified 501(c)(3) tax-exempt organization.
*Red Dress™ DHHS, Go Red™ AHA; National Wear Red Day ® is a registered trademark.

  • PUTTING PATIENTS FIRST National Health Council Standards of Excellence Certification Program
  • BBB Accredited Charity
  • Comodo Secured